The YF-22 was first operated in the Skully Islands insurrection by both the insurrection and the Scarface Squadron. It was the choice of aircraft for Hal, a member of the Scarface Squadron.[1]
The 'F-22' designation was likely meant to refer to the production variant, which was first shown in Ace Combat 04: Shattered Skies. With the release of Assault Horizon Legacy, the Lightning II's appearance in Ace Combat 2 is considered non-canonical.
One of the F-22A Raptor's alternate paint schemes in some games are based on the YF-22.
In Ace Combat 2, there is a texture glitch associated with the Enemy Type A YF-22; The jet nozzles on the craft are transparent, allowing one to see through it. None of the other textures have this issue. This is most easily seen in the Model Viewer.